A delivery system which offers a scalable, natural, Generally Regarded As Safe (GRAS) approved solution for the oral delivery of metabolic peptide cargo to specific areas of the gut and into systemic circulation for the treatment of diabetes, obesity and other metabolic diseases

Metabolic Diseases – A Fast Growing Market

GLP-1R Agonist market expected to exceed $150bn by 2031

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Worldwide obesity has nearly tripled since 1975 & obesity treatment could quickly become a top-12 global therapy

Proof-of-technology clinical trial preparation underway

Trial to determine that a Glucagon-like Peptide 1 receptor (GLP-1R) agonist can be delivered orally in humans expected to commence in H1 2024

The effectiveness of the technology in successfully delivering APIs across the gut wall and eliciting the required biological response / clinical benefit has been demonstrated in small scale Proof of Concept human clinical trials.

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In December 2022, we acquired an exclusive license to InsuCaps’ (sister company of AnaBio Technologies) oral delivery technologies for treating metabolic conditions such as obesity, pre-diabetes and diabetes. Obesity alone costs the US healthcare system c. $173bn a year.

Oral Delivery solves many problems

The Challenge

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Potential benefits of applying our patented technology
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Overcoming challenges

  • Adaptable technology to tailor release in specific gut regions
  • Natural biodegradability using a food-grade encapsulation platform
People Stack

Mass access to treatment

  • Easier to administer than an injection
  • Reduced need for trained staff
  • No needle phobia or biohazard waste
  • People are more willing to take an oral product
Transport

Manufacturing & distribution

  • Often easier to produce
  • Superior thermostability
  • Reduced need for cold chain
  • Longer shelf life
  • Easier distribution

We are open to partnering, contact our team at

Partnering@PoolbegPharma.com